John P Kirwan Selected Research

3-methylhexane

11/2021

The breath print represents a novel biomarker of malnutrition in pulmonary arterial hypertension: A proof of concept study.

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John P Kirwan Research Topics

Disease

87	Insulin Resistance 02/2024 - 06/2002
43	Type 2 Diabetes Mellitus (MODY) 01/2024 - 01/2007
37	Obesity 02/2024 - 02/2003
30	Weight Loss (Weight Reduction) 11/2023 - 06/2009
25	Inflammation (Inflammations) 01/2022 - 09/2005
23	Body Weight (Weight, Body) 12/2023 - 07/2003
15	Hyperglycemia 01/2021 - 02/2003
14	Non-alcoholic Fatty Liver Disease 12/2023 - 11/2011
9	Glucose Intolerance 12/2017 - 06/2009
9	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 12/2014 - 09/2005
8	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2018 - 01/2009
6	Neoplasms (Cancer) 11/2022 - 12/2013
5	Breast Neoplasms (Breast Cancer) 11/2022 - 01/2015
5	Fibrosis (Cirrhosis) 09/2020 - 03/2013
4	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2021 - 01/2014
4	Gestational Diabetes (Gestational Diabetes Mellitus) 03/2008 - 06/2002
3	Overweight 01/2023 - 12/2006
3	Hypertension (High Blood Pressure) 01/2022 - 06/2013
3	Familial Primary Pulmonary Hypertension 01/2020 - 02/2017
3	Fatty Liver 01/2017 - 08/2012
2	Pulmonary Arterial Hypertension 11/2021 - 01/2020
2	Diabetic Nephropathies (Diabetic Nephropathy) 09/2020 - 06/2020
2	Morbid Obesity 10/2019 - 06/2016
2	Prediabetic State (Prediabetes) 02/2019 - 01/2019
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 12/2011
2	Hyperinsulinism (Hyperinsulinemia) 01/2016 - 12/2010
2	Atherosclerosis 01/2015 - 09/2010
2	Abdominal Obesity 01/2014 - 10/2011
2	Hyperlipidemias (Hyperlipidemia) 11/2013 - 11/2011
1	Obstructive Sleep Apnea 02/2024
1	Anemia 01/2024
1	Flatulence 04/2023
1	Hepatocellular Carcinoma (Hepatoma) 08/2022
1	Cachexia 01/2022

Drug/Important Bio-Agent (IBA)

76	Glucose (Dextrose)FDA LinkGeneric 02/2024 - 06/2002
43	Insulin (Novolin)FDA Link 01/2021 - 06/2002
23	LipidsIBA 01/2021 - 07/2003
13	Triglycerides (Triacylglycerol)IBA 01/2021 - 01/2009
11	LeptinIBA 01/2021 - 07/2002
11	AdiponectinIBA 01/2021 - 07/2007
10	Proteins (Proteins, Gene)FDA Link 09/2020 - 09/2004
7	Biomarkers (Surrogate Marker)IBA 01/2022 - 05/2011
7	AdipokinesIBA 01/2021 - 05/2006
7	CeramidesIBA 01/2019 - 02/2009
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2012 - 07/2002
6	C-PeptideIBA 01/2023 - 07/2003
6	Nonesterified Fatty Acids (NEFA)IBA 11/2014 - 08/2009
5	Interleukin-6 (Interleukin 6)IBA 01/2022 - 10/2007
5	IncretinsIBA 01/2021 - 07/2010
5	CytokinesIBA 12/2014 - 09/2010
4	salicylhydroxamic acid (SHAM)IBA 01/2021 - 09/2010
4	HDL CholesterolIBA 01/2021 - 10/2011
4	Blood Glucose (Blood Sugar)IBA 06/2020 - 09/2005
4	Fatty Acids (Saturated Fatty Acids)IBA 01/2020 - 01/2012
4	CholesterolIBA 01/2019 - 11/2011
4	Hormones (Hormone)IBA 01/2019 - 07/2002
4	Peptides (Polypeptides)IBA 01/2016 - 06/2009
4	LipopolysaccharidesIBA 12/2014 - 09/2005
3	LigandsIBA 01/2022 - 07/2012
3	Adenosine Triphosphate (ATP)IBA 10/2021 - 09/2013
3	Phenobarbital (Luminal)FDA Link 10/2021 - 01/2018
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 01/2006
3	Messenger RNA (mRNA)IBA 09/2020 - 03/2008
3	alpha-2-HS-GlycoproteinIBA 06/2020 - 10/2013
3	CarbohydratesIBA 01/2018 - 02/2003
3	PalmitatesIBA 11/2017 - 08/2009
3	LDL Lipoproteins (beta Lipoproteins)IBA 10/2013 - 11/2011
2	PhytochemicalsIBA 11/2022 - 01/2013
2	PyrazinesIBA 01/2022 - 10/2021
2	phospholipid emulsion soybean oil (Intralipid)IBA 01/2021 - 08/2009
2	Protons (Proton)IBA 01/2021 - 11/2019
2	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2021 - 01/2016
2	Receptor for Advanced Glycation End ProductsIBA 06/2020 - 12/2017
2	KetonesIBA 01/2020 - 01/2020
2	Endothelin-1 (Endothelin 1)IBA 02/2017 - 01/2016
2	InflammasomesIBA 12/2016 - 01/2015
2	CalciumIBA 12/2015 - 08/2011
2	Vitamin D FDA LinkGeneric 12/2015 - 08/2011
2	C-Reactive ProteinIBA 01/2015 - 11/2014
2	Testosterone (Sustanon)FDA Link 12/2014 - 01/2013
2	Androstenedione (4 Androstene 3,17 dione)IBA 12/2014 - 07/2009
2	HDL LipoproteinsIBA 03/2014 - 10/2013
2	Plasminogen Activator Inhibitor 1IBA 01/2013 - 07/2009
2	Pentoxifylline (Trental)FDA LinkGeneric 10/2012 - 11/2011
2	Nicotinamide PhosphoribosyltransferaseIBA 01/2010 - 06/2009
2	NF-kappa B (NF-kB)IBA 07/2009 - 04/2006
1	Metformin (Glucophage)FDA LinkGeneric 02/2024
1	IronIBA 04/2023
1	OligosaccharidesIBA 04/2023
1	Ghrelin ReceptorsIBA 01/2022
1	activin AIBA 01/2022

Therapy/Procedure

32	Bariatric Surgery 01/2024 - 03/2010
27	Gastric Bypass (Roux-en-Y Gastric Bypass) 12/2023 - 03/2010
16	Glycemic Control 01/2024 - 04/2012
16	Therapeutics 12/2023 - 04/2012
6	Gastrectomy 01/2021 - 04/2012
5	Caloric Restriction 06/2020 - 01/2009
3	Drug Therapy (Chemotherapy) 10/2021 - 12/2013
1	Chemoprevention 11/2022
1	Obesity Management 08/2022